Publications
Roddick KM, Habib EB, Brown RE, Balc脹 F (Submitted) Interval Timing is altered in male Nrxn1+/- mice: A Model of Autism Spectrum Disorder. Autism Research.
Roddick KM, Schellinck HM, Brown RE (Submitted) Motor deficits in the McGill-R-Thy1-APP transgenic rat model of Alzheimers Disease. Behavioural Processes.
Lu H, Roddick KM, Ge Y, Zuo L, Zhang P, Lam O, Marsh K, Wong ROL, Brown RE, Craig AM (2025) Targeted splicing approach for alleviation of a neurexin 1 haploinsufficiency model. Molecular Psychiatry.
Roddick KM, Brown RE (2024) An Overview of Methods for Measuring Olfaction in Rodents. Symposium on "Olfactory Memory. Proceedings of the 13th International Conference on Methods and Techniques in Behavioral Research, Aberdeen, Scotland. Editors: Andrew Spink, Gernot Riedel, Khiet Truong, & Lianne Robinson, pages 80-86.
Brown RE, Habib EB, Schnare OK, Roddick KM (2024) Pavlovian conditioned odour preferences in mice. Symposium on "Olfactory Memory. Proceedings of the 13th International Conference on Methods and Techniques in Behavioral Research, Aberdeen, Scotland. Editors: Andrew Spink, Gernot Riedel, Khiet Truong, & Lianne Robinson, pages 87-90.
Ortbus W, Roddick KM, Brown RE (2024) Olfactometer Methodologies in Rodent Olfaction Research: What can we test about learning and memory? Symposium on "Olfactory Memory. Proceedings of the 13th International Conference on Methods and Techniques in Behavioral Research, Aberdeen, Scotland. Editors: Andrew Spink, Gernot Riedel, Khiet Truong, & Lianne Robinson, pages 91-96.
Gendron WH, Fertan E, Roddick KM, Wong AA, Maliougina M, Hiani YE, Anini Y, Brown RE (2024) Intranasal insulin treatment ameliorates spatial memory, muscular strength, and frailty deficits in 5xFAD mice. Physiology & Behavior, 281, 114583.
Roddick KM, Schellinck HM, Brown RE (2023) Serial reversal learning in an olfactory discrimination task in 3xTg-AD mice. Learning & Memory. 30(12), 310319.
Brown RE, Schnare OK, Habib E, Roddick KM (2023) Development of a one-day test of olfactory learning and memory in mice. In: Schaal, B., Keller, M., Rekow, D., Damon, F. (eds) Chemical Signals in Vertebrates 15. CSiV 2024. Springer, Cham.
Lu H, Zuo L, Roddick KM, Zhang P, Oku S, Garden J, Ge Y, Bellefontaine M, Delhaye M, Brown RE, Craig AM (2023) Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors. Cell Reports. 42(7), 112714.
Fertan E, Wong AA, Montbrun TSG, Purdon MK, Roddick KM, Yamamoto T, Brown RE (2023) Early postnatal development of the MDGA2+/- mouse model of synaptic dysfunction. Behavioural Brain Research. 452, 114590.
Roddick KM, Fertan E, Schellinck HM, Brown RE (2022) A Signal Detection Analysis of Olfactory Learning in 12-Month-Old 5xFAD Mice. Journal of Alzheimers Disease. 88(1), 3744.
Bailey LM, Bodner GE, Matheson HE, Stewart BM, Roddick KM, ONeil K, Simmons M, Lambert AM, Krigolson OE, Newman AJ, Fawcett JM (2021) Neural correlates of the production effect: An fMRI study. Brain and Cognition. 152:105757.
Gendron WH, Fertan E, Pelletier S, Roddick KM, OLeary TP, Anini Y, Brown RE (2021) Age related weight loss in female 5xFAD mice from 3 to 12 months of age. Behavioural Brain Research. 406:113214.
Roddick KM, Roberts AD, Schellinck HM, Brown RE (2016) Sex and genotype differences in odor detection in the 3xTg-AD and 5XFAD mouse models of Alzheimers disease at 6 months of age. Chemical Senses. 41(5):433-440.
Roddick KM, Schellinck HM, Brown RE (2014) Olfactory delayed matching to sample performance in mice: Sex differences in the 5XFAD mouse model of Alzheimer's disease. Behavioural Brain Research. 270:165-170.
Education
PhD Psychology/Neuroscience, Dalhousie University
MSc Psychology/Neuroscience, Dalhousie University
BSc Neuroscience, Dalhousie University
Teaching
- PSYC-2121: Behavioural Modification
- PSYC-3111: Conditioning
- PSYC-3151: Drugs & Behaviour
- PSYC-4101: Advanced Topics in Behavioural Neuroscience
- BIPS-4121: Advanced Topics in Biopsychology
- PSYC-4991 Neurobiology of Learning & Memory
Research
My research is centred on using transgenic mice as a powerful tool to unravel the complexities of diseases and conditions, and assessing the neurological basis of behaviour, with a focus on the use of olfactory based tasks to evaluate learning and memory. The core of my research aims to bridge the gap between molecular biology and behavioural science. Utilizing transgenic rats and mice allows for the manipulation of specific genes, enabling a nuanced exploration of the genetic basis of behaviour and its implications for disease susceptibility and manifestation. By employing transgenic rodent models, I aim to unravel the neurobiological underpinnings of psychological and neurological disorders and diseases, translating these findings into valuable insights for the development of targeted interventions and therapies. Through a combination of quantitative methodologies, interdisciplinary collaboration, and a translational focus, I aim to advance our understanding of the genetic and behavioural factors underlying neuropsychological disorders.